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Antibiotics are the first-line drugs for the treatment of infectious diseases. Antibacterial agents are widely used in such fields of medicine, as surgery, urology, ophthalmology, gynecology and gastroenterology. To date, antibiotics are the most numerous class of medicines.
Antibiotics are a huge group of bactericidal drugs that differ by the spectrum and mechanism of action.
By the spectrum of action, antibiotics are of:
- narrow spectrum of action – inhibit the growth of gram-positive microorganisms;
- wide spectrum of action – inhibit the growth of both gram-positive and gram-negative microorganisms.
The wider the spectrum of the drug action, the more infections it can cure. The main disadvantage of broad-spectrum antibiotics is that disruption of intestinal flora takes place together with the destruction of infectious agents. Intestinal bacteria play an important role in digestion processes, so their neutralization with antibiotics causes such condition, as dysbacteriosis.
By the action mechanism, antibiotics are:
- bactericidal (cause the death of infectious microorganisms)
- bacteriostatic (suppress the ability of microorganisms to reproduce)
Some antibiotics, for example, Mupirocin, possess both bacteriostatic and bactericidal action.
Despite the differences in chemical structures, the spectrum of activity and mechanisms of action, all antibiotics:
- act directly on the cell membrane or prokaryotic cell of bacteria;
- lose antibacterial and bactericidal activity in prolonged use.
Since antibiotics are the most numerous class of pharmacological drugs, they are available for sale in almost any pharmacy. In pharmacy chains and online pharmacies, you can find:
- Oral antibiotics (tablets, capsules, powders, suspensions, etc.);
- Parenteral antibiotics (injections, infusions, rectal suppositories, etc.);
- Topical medicines with antibacterial activity (creams, ointments, eye drops, etc.).
Some antibiotics are sold in regular pharmacies without a prescription. Nevertheless, treatment of serious infectious diseases requires the use of antibacterial drugs, which are dispensed only with a medical prescription of the treating doctor. If a patient needs urgent antibiotic therapy, and he does not have a prescription, he can order antibiotics online.
The range of medicines in online pharmacies is much wider than that in the usual drugstores. In addition, the cost of antibacterial drugs in online pharmacies is below the market price. Thus, with frequent recurrences of infection, men and women buying antibiotics online significantly save their money.
In online pharmacies, you can find brand antibiotics and their generic versions. Branded antibacterial drugs can cost both more and less expensive than generics. Therefore, when buying antibiotics, it is necessary to pay attention not to their trade name, but to the name of the antibacterial agent in their composition.
It should be noted that not all antibiotics help to successfully cure infectious diseases. The main reason for the ineffectiveness of antibacterial therapy is the ability of microorganisms to develop resistance to the action of antibiotics. The reasons for the formation of resistance to the action of antibacterial drugs can be:
- prolonged and unreasonable use of antibiotics;
- independent administration of medicines without them being prescribed by the attending physician;
- use of a drug that is not intended to treat the particular infection.
The issue of the microorganisms resistance to the action of antibiotics has arisen since the introduction of drugs into clinical practice and still remains relevant.
Sooner or later, microbes become immune to the therapeutic effect of one or another antibiotic. Therefore, scientists are forced to continuously hold very laborious and expensive studies, creating new drugs to overcome resistance to antibiotics.
To reduce the risk of antimicrobial resistance (AMR), it is necessary to consider the principles of rational antibiotics use:
- avoid prescribing drugs with unproved efficacy against a particular infection;
- assess the efficacy of the antimicrobial therapy within the first 2-3 days after the treatment initiation;
- observe the prescribed regime of drug administration – daily dose, frequency of administration, duration of the antimicrobial therapy.
For the antibiotic therapy to end without complications, antibiotics should not be bought for other purposes, except for the treatment of bacterial infections.
Many patients make the common mistake of taking antibiotics to treat respiratory viral diseases, like colds, flu or bronchitis.
Antibacterial drugs are not designed to fight viruses. Antibiotics should be used only against those respiratory diseases that were caused by a bacterial infection – sore throat, sinusitis or otitis.
Other common mistakes that can be made by patients during the treatment of infectious diseases are:
- simultaneous use of several antibiotics;
- alcohol consumption during antibiotic therapy;
- improper selection of the release form or dosage, non-compliance with recommendations for use.